ABSTRACT
Factors on DNA Methylation in Rodents ............................. 47 3.4.2 Effects of Folate Deˆciency and Supplementation on DNA
Methylation in In Vitro Systems .........................................................48 3.4.3 Effects of Folate Status on DNA Methylation in Human Studies ...... 49
3.4.3.1 Effect of Folate Deˆciency and Supplementation on DNA Methylation in Human Clinical Trials ....................... 49
3.4.3.2 Effects of Folate Status on Genomic DNA Methylation in Human Observational Studies ......................................... 53
3.4.3.3 Effects of Folate Status on Gene-Speciˆc DNA Methylation in Human Observational Studies .....................56
