ABSTRACT
Lessons from IRP Mutant Mice ................................................377 17.2 Interplay between Nitric Oxide (NO) and IRPs ...................................379
17.2.1 NO as a Modulator of [Fe-S] Cluster-Containing Proteins ......379 17.2.2 NO and the Post-Translational Regulation of IRP1 Activities ......380 17.2.3 Mechanism Underlying NO Modulation of IRP1
RNA-Binding Activity ...............................................................381 17.2.4 Regulation of IRP1 Protein Levels by NO ................................383 17.2.5 Modulation of IRP2 by NO .......................................................384 17.2.6 Functional Impact of the NO/IRP Regulatory System on
Ferritin and TfR Expression ......................................................385 17.3 A Look Ahead .......................................................................................386
