ABSTRACT
Among the classes of drugs and biological agents employed to reduce serum
urate levels, uricosuric drugs are those that share the property of increasing renal
uric acid excretion (1). In this chapter, we review drugs prescribed specifically for
their uricosuric properties, including sulfinpyrazone, probenecid, and benzbro-
marone, as well as those used as adjuvants in treating hyperuricemia, such as
losartan and fenofibrate. Specific attention is given to the practical issues
regarding uricosuric agents: who should take them and how they should
be prescribed.
