ABSTRACT
An open-label first clinical dermatologic trial was performed to study the effective ness of the material on nonbum hypertrophic scars and keloids in a dermatologic setting. The scars studied were secondary to either a surgical procedure or traumatic insult. Sixteen scars were initially studied. Each of the participants wore the topical silicone gel sheet for a minimum of 12 hours per day for up to 3 months. The following parameters were evalu ated: change in scar thickness, change in scar color toward normal, and overall effective ness. All study participants noted that the material was easy to use and there were no ad verse reactions. Moderate improvement in the thickness of the scar was noted in 81.25% and in scar color toward normal skin in 75%. Physician evaluation revealed complete res olution or moderate improvement in thickness in 56.25% and color change in 75%. In a comparison of hypertrophic scars and keloids, the keloids were more apt to be reduced in thickness according to the patients’ evaluations. Color changes were fairly constant be tween the two groups. Positive changes were noted in all the scars both by the patients and by physician evaluation (Fig. 1-4).
