chapter  3
96 Pages

Physiological Principles of Cardiac Toxicology

I had written a chapter on the effects of some cardiotoxic agents on the electrical properties of myocardial cells for the 2-volume book on cardiac toxicology edited by Dr. Tibor Balazs and published in 1981. When Dr. Steven Baskin asked me to update that chapter for inclusion in a book on cardiac toxicology that he was editing, and which was to be dedicated to Dr. Balazs, I felt motivated to do so. The present article is the updated chapter on the electrophysiological principles and factors necessary for an understanding of how many cardiotoxic agents affect the heart.