ABSTRACT

Some chemicals that are stored may remain in the body for years without exhibiting appreciable e–ects. One such chemical is DDT. Accumulation or buildup of free chemicals may be prevented, until the storage sites are saturated. Selective storage limits the amount of foreign chemicals to be excreted, however. Since bound or stored toxicants are in equilibrium with their free forms, a chemical will be released from the storage site as it is metabolized or excreted. On the other hand, accumulation may result in illnesses that develop slowly, as is the case with «uorosis, or lead and cadmium poisoning.