Fluorescence Resonance Energy Transfer-Based Sensors for Bioanalysis
Biosensors have been valuable analytical tools for several decades, with glucose sensing being the most impressive success story of biosensor technology.
Recent developments in the field of biosensors enable their employment in new applications primarily focusing on real-time monitoring of bimolecular interactions. For example, biosensors have been used to monitor processes such as ligand fishing,
signal transduction in cells,
and protein conformation changes and aggregation.