ABSTRACT

Acknowledgments ........................................................................................................................ 380

References .................................................................................................................................... 380

The sol-gel process and its use in the encapsulation of biomolecules of various kinds have recently

seen important developments. Since its first introduction over two decades ago, sol-gel encapsula-

tion has opened intriguing new ways to immobilize biological materials that offer an immense

potential for the design of a large variety of applications. A great number of biomolecules,

including enzymes, antibodies (Abs) (monoclonal, polyclonal, recombinant, and catalytic),

DNA, RNA, and live animal, plant, bacterial, and fungal cells as well as whole protozoa have

been encapsulated and then tested and implemented as optical and electrochemical sensors as well

as core components of diagnostic, chromatographic, and catalytic devices.