ABSTRACT
Carcinogenesis .......................................................................................580 28.2.1 Increased Generation of Acetaldehyde....................................580 28.2.2 Induction of Cytochrome P4502E1 and Activation of
Chemical Procarcinogens ........................................................582 28.2.3 Generation of Reactive Free Radicals That Cause DNA
Damage ....................................................................................584 28.2.4 Impairment of Immune Function ............................................585 28.2.5 Induction of Cell Hyperproliferation That Promotes
Genomic Instability .................................................................586 28.2.6 Deregulation of Apoptosis and Promotion of
Tumorigenesis ..........................................................................587 28.2.7 Impaired Nutritional Status .....................................................588
