ABSTRACT
Skincare products that affect wrinkles are a reality and are well established in consumer, practitioner, and corporate perspectives. In the broadest definition, ‘‘products’’ range from classic and simple cosmetic preparations through vitamins, antioxidants, topical and oral cosmeceutical and pharmaceutical preparations, and even to surgical and laser interventions. Substantiation of product effect ranges from user testimonials through rigorous consumer testing and claim substantiation to classical pharmaceutical trials. Methodologies vary from casual visual and tactile observations to elaborate scoring of specific clinical parameters, and may be enhanced and embellished by use of many sensitive, accurate, reproducible, and validated instrumental techniques. The topic is currently exceptionally rich and expansive.
