ABSTRACT

Occlusion occurs on a regular basis from diapers and feminine hygiene products to clothes, gloves, and bandages. Originally felt to be a neutral intervention, occlusion per se was found to be active on the skin when studies evaluated the effect of occlusion per se. Our aim is to broadly capture research in medical disciplines related to the effect of occlusion on human skin, both healthy and diseased, and to illustrate the current knowledge regarding occlusion as an active agent.