ABSTRACT

I. Introduction 361

II. Origins of Physiological Tremor 362

A. Historical Note 362

B. Mechanical Factors in Physiological Tremor 363

C. Stretch Reflex in Physiological Tremor 364

D. Central Oscillators in Physiological Tremor 364

III. Enhanced Physiological Tremor 365

A. Description 365

B. Mechanism of Enhanced Physiological Tremor 365

C. Clinical Aspects of Enhanced Physiological Tremor 366

IV. Conclusion 367

References 367

I. INTRODUCTION

Physiological tremor can be broadly defined as an involuntary and continuous

oscillation of any limb segment occurring in otherwise normal subjects (1-3).

This tremor type can be present when the limb segment is at rest, held against

gravity, in motion, or under isometric contraction. The frequency of physiological

tremor varies widely in different body parts, although 8-12 Hz oscillation has

traditionally been evoked as the frequency range (4). The amplitudes of these

oscillations are generally small such that normal finger tremor can barely be

seen with the naked eye. However, by means of either optical magnification or

mechanical-electrical transducers, such as accelerometers, physiological tremor

can be recorded in any joint or muscle that can oscillate (3,4). Another type of

tremor that can occur in normal subjects is enhanced physiological tremor, but

unlike physiological tremor, this tremor type is easily visible to the naked eye,

and can be quite symptomatic.