ABSTRACT

Many chemical manufacturing processes involve solid particles, either as feeds or products or as internal process enhancers such as catalysts. These processes span a range of industries including pharmaceuticals, pigments, agricultural chemicals, and foods, as well as polymers. Solution crystallization, where a solvent (or a mixed solvent) with one or more solutes is involved, is a critical operation in solids processing because it can strongly affect the characteristics of a solid product. The crystallization step can perform several functions in a process, including separation or purification, as well as particle formation.