ABSTRACT

Significant progress has been achieved in clinical islet transplantation in the past two decades (1-7). Islet transplantation continues to gain promise as a potential cure for patients with Type 1 diabetes mellitus (8). Numerous technological improvements have been introduced in pancreas procurement (9) and preservation (10-12), islet isolation (13-15), purification (16-18), assessment (19,20), and culture (21), as well as in the management of islet transplant recipients (1-6).