ABSTRACT
Dry powder processing equipment can be cleaned through the use of clean-in-place
(CIP) systems. As described in this book, there are a number of advantages to using
CIP systems for cleaning many types of biopharmaceutical equipment including:
controls of cleaning parameters, control of variability in the cleaning process
(consistency), and the ability to more easily validate the cleaning process. The
ability to establish controlled conditions of time, concentration, and temperature via
application of a CIP system has been demonstrated to be superior to manual
cleaning under any conditions.
