ABSTRACT
Previous chapters of this book have identified the important variables that
determine the efficacy of the clean-in-place (CIP) procedure, specifically time,
temperature, concentration, and physical action. The first three are controllable
and are subject to variations due to hardware and software failures. Physical action
is initially determined by engineering design but may be affected by variations in
flow and pressure caused by hardware or software failure. This chapter is intended
to provide troubleshooting suggestions only for qualified CIP circuits, and
generally on the basis of human machine interface (HMI) alarms to convey basic
information regarding a CIP program failure. It is assumed that CIP circuit design
issues have been resolved prior to or during commissioning and that the CIP system
has been properly commissioned and qualified, meaning that, at one point in time
prior to the CIP circuit failure; the CIP circuit had been known to run well with
properly selected recipe parameters proven capable of removing the expected soil,
and thus restore the equipment to a visually or swab analysis clean state.
