ABSTRACT
Chapter 5 focused on the anatomical, physiological, and behavioral properties of limbic structures with respect to their roles in the regulation of aggression and rage behavior. A large number of the studies that contributed to our knowledge linking the limbic system to aggression and rage were based on the application of mainly electrical, and to a lesser extent, chemical stimulation of these structures. Accordingly, a series of studies was conducted utilizing microstimulation of different regions of the limbic system in conjunction with (
C)2-deoxyglucose (2-DG) autoradiography. As pointed out in earlier chapters, a close relationship exists between functional activity and incorporation of 2-DG into neurons. For this reason, this method was used to identify the regions of the brain that are demonstrably activated following discrete stimulation of different sites within each of the limbic structures. This information was deemed valuable in providing insight into the anatomical substrates involved in limbic modulation of aggression and rage behavior.
