ABSTRACT
The development of anatomical and functional imaging modalities such as
computer tomography (CT), magnetic resonance imaging (MRI), functional
MRI (fMRI), and positron emission tomography (PET) has contributed signif-
icantly to Alzheimer’s disease (AD) research and the understanding of the dis-
order. Although nothing conclusive has been established, imaging techniques
have gained popularity due to the relative ease with which neurological mark-
ers such as neuronal loss, atrophy of brain tissue, and reduced blood perfusion
can be converted to visual markers on brain images (Xanthakos et al., 1996;
Petrella et al., 2003).
