ABSTRACT

INTRODUCTION In March 2008, a Science Advisory Panel (SAP) of the United States Environmental Protection Agency (U.S. EPA) met to consider a battery of tests proposed by the agency as a screen for the identification of endocrine disrupting chemicals (EDCs). The SAP received documents and heard statements provided by U.S. EPA officials and representatives from the public. After discussion and evaluation of the materials provided, the panel recommended that the U.S. EPA adopt the entire battery as proposed, to constitute an initial level of screening (called Tier 1) of substances for their ability to interact with the estrogen, androgen, and thyroid (EAT) hormone systems, or with the feedback regulation of the hypothalamic-pituitary-gonadal (HPG) axis. Details of this SAP meeting and the text of its report can be found on the U.S. EPA Web site (1).