ABSTRACT

NECESSITY FOR DEVELOPMENT OF SCREENING FOR CHEMICALS AFFECTING MALE REPRODUCTIVE ENDPOINTS Several cases have been shown where local and high-level exposure to environmental contaminants has resulted in adverse effects in wildlife (1-3). Therefore, there are particular concerns that ambient levels of chemicals may interact with the endocrine system to cause detrimental effects in humans (2). However, considerable uncertainty exists regarding the relationship(s) of these exposures with adverse health outcomes in humans (4). This underlies the present global consensus that screening and testing protocols should be developed to provide sufficient information to allow for accurate classification of endocrine disrupting chemicals (5,6).