ABSTRACT

Iron (Fe) is an essential element involved in a variety of cellular processes critical for life, including oxygen transport, energy generation, and DNA synthesis.1-3 This is due to the unique redox activity of iron, which is able to act as an electron donor or acceptor by cycling between the ferric (Fe3+) and ferrous (Fe2+) states. Importantly, iron can participate in the oxidation-reduction process known as the Haber-Weiss reaction where hydrogen peroxide reacts to form the hydroxide anion and the reactive oxygen species (ROS), the hydroxyl radical.4