chapter  1
6 Pages

Introduction to time to event methods

Rendered to “The dose makes the poison, ” Paracelsus’ admonition is a helpful reminder that both quality and quantity of an administered substance determines whether a poisoning will occur. Unfortunately, some toxicologists forget the context of this statement, remaining convinced that dose or concentration quantification is the most crucial task in determining exposure consequences. This preoccupation extends to toxicologists interested in consequences to ecological receptors of environmental exposures.