Chapter Fish Allergens
Probably the most known and most studied major sh allergen is named Gad c 1 (allergen M) (Poulsen et al. 2001). This highly water-soluble protein from Baltic cod sh (Gadus callarias) belongs to a family of calcium-binding proteins commonly known as parvalbumins (Poulsen et al. 2001). Currently, more than 20 parvalbumins from various sh species are classi ed as major allergens and have been adopted to the International Union of Immunological Societies (IUIS) allergen nomenclature, e.g., Sal s 1 (Atlantic salmon, Salmo salar) (Lindstroem et al. 1996), Tra j 1 (horse mackerel, Trachurus japonicus), Gad m 1 (Atlantic cod, Gadus morhua) (Das Dores et al. 2002b), Sco j 1 (mackerel, Scomber japonis), Sco a 1 (mackerel, Scomber australasicus), Sco s 1 (mackerel, Scomber scombrus) (Hamada et al. 2002b), Thu o 1 (bigeye tuna, Thunnus obesus), Ang j 1 (Japanese eel, Anguilla japonica) (Shiomi et al. 1999), The c 1 (pollock, Theragra chalcogramma), and Cyp c 1 (carp, Cyprinus carpio) (Wopfner et al. 2007).