ABSTRACT

INTRODUCTION Immunotoxicology is a scientific discipline focused on the evaluation of potential adverse effects of xenobiotics (chemicals, drugs, and biotechnology-derived products) on the host immune mechanisms that can lead to harmful changes in the immune system. Unintended immunosuppression can lead to an increased susceptibility to infectious diseases and tumorigenesis and unintended immunostimulation can lead to the induction of hypersensitivity reactions, or an increased incidence of autoimmune disease.