chapter  11
30 Pages

Dermal Exposure, Uptake, and Dose

Methods..................................................................................................271 11.10.2

In Vivo

Methods ..................................................................................................272 11.11 Highlighted Dermal Dose Examples.................................................................................273 11.12 Conclusion .........................................................................................................................274 11.13 Questions for Review ........................................................................................................275 Glossary of Terms ..........................................................................................................................276 References ......................................................................................................................................278

The dermal route of exposure and dose to toxic agents has gained recognition over the last decade as being important for certain population groups and certain classes of chemicals. This chapter introduces the field of dermal exposure and dose, and all its related components, such as the human skin, the factors affecting percutaneous absorption, the mechanisms of exposure, techniques used in the field for directly measuring dermal exposure, and the