ABSTRACT

Capillary electrophoresis (CE) is a microscale analytical separation technique that has matured rapidly over the past 20 years since the groundbreaking publications of Jorgenson and Lukacs.1,2 Biomedical applications of CE are a leading factor driving the development of what has now evolved into a broad family of related separation techniques. Certainly the most prominent biomedical application of CE is the sequencing of the human genome.3 e accelerated achievement of this goal depended on CE separations.3-5 From 1981 through the writing of this text, more than 14,000 papers were published that included CE and related techniques. A survey of this literature over the past 12 months indicates that more than 70% of these reports include bioanalytical applications of CE.