ABSTRACT
Acknowledgments .................................................................................................. 101
Copper/quinone containing amine oxidases (EC 1.4.3.6, amine: O2 oxidoreductase [deaminating, copper containing]) have been intensively studied since the 1950s. They appear to be widespread enzymes and are found in bacteria, yeast and fungi, plants, sh, birds, and mammals. The rst gene encoding a copper amine oxidase from the yeast Hansenula polymorpha (now Pichia angusta) was cloned and sequenced in 1989 (Bruinenberg et al., 1989) followed by genes from lentil seedlings, Lens esculenta (Rossi et al., 1992), bacteria, Klebsiella aerogenes (Yamashita et al., 1993) and Arthrobacter strain P1 (Zhang et al., 1993), rat colon (Lingueglia et al., 1993), human kidney (Novotny et al., 1994), Escherichia coli K12 (Azakami et al., 1994), bovine serum (Mu et al., 1994), Arthrobacter globiformis (Tanizawa et al., 1994; Choi et al., 1995), pea seedlings (Tipping and McPherson, 1995), and several others.
