ABSTRACT

The signicance of increased plasma levels of BzAO occurring in diabetes patients is far from clear. Increased plasma BzAO levels are correlated with glycated hemoglobin (Boomsma et al., 1995 and 2005a; Xu et al., 2005) Moreover circulating BzAO has also been proposed as an independent prognostic marker for mortality in

heart failure (Boomsma et al., 2000b), suggesting a relationship of plasma enzyme activity, the duration of diabetes, and its cardiovascular complications.