ABSTRACT
The wide dispersal into the environment of a huge number of chemicals potentially able to perturb the normal hormonal processes in human or wildlife focused interest on methods for in silico prediction of potential toxicity, to help in priority setting before costly and time-consuming in vitro and in vivo assays. In this eld, CoMFA (comparative molecular eld analysis) and CoMSIA
11.1 Introduction .................................................................................................296 11.2 Comparative Molecular Field Analysis Methods: CoMFA, CoMSIA ........299
