ABSTRACT

Grodzinsky, Melcher, Yannas and coworkers out of MIT were the first to present coherent theories on the electromechanics of deformable, charged polyelectrolyte biomembranes as early as 1973 and their efforts have continued to the present time through the works of Grimshaw et al. (1989, 1990). Their approach has been based on the effect of movement of charged species, electrodiffusion phenomena, dissociation of membrane charge groups, intramembrane fluid flow, electro-osmotic drag, and mechanical deformation of membrane matrix-all due to charge redistribution within the polymeric network.