ABSTRACT
The systemic retinoids possess a remarkable range of activities and clinical applications. They are an important form of therapy for patients with more severe and resistant types of psoriasis. In general, systemic retinoids are used most effectively in the treatment of plaque psoriasis in combination with other forms of therapy, such as phototherapy or other systemic agents. With generalized pustular psoriasis, they are effective as monotherapy and are frequently helpful for the control of exfoliative psoriasis.
