ABSTRACT

Inhalation drug therapy has received increased interest in recent years as an attractive route of administration for both local and systemic effects. The advantages of pulmonary drug delivery include noninvasiveness, high surface area available for absorption, high blood ow, and avoidance of rst-pass metabolism. However, the lungs are designed to protect the body against the environment making targeted drug delivery to the lungs challenging for pharmaceutical scientists (Azarmi et al. 2008; Rytting et al. 2008; Scheuch et al. 2006).