ABSTRACT

Endocrine tumors in children pose a number of fundamental questions: Is the tumor a nonfunctioning, functioning, or hyperfunctioning entity? Is it a malignant or a benign process or a hyperplasia responsive to physiological regulations? Apart from clinical presentation, the answers to these questions often depend on specific hormonal biochemical, radiological, and histopathologic findings. Consequently, the optimal assessment and management of these patients remains a challenging task and must include the efforts of endocrinologists, oncologists, surgeons, and other support personnel.