ABSTRACT
I. Introduction Community-acquired pneumonia (CAP), Hospital-acquired (or nosocomial) pneumonia (HAP), ventilator-associated pneumonia (VAP), and health care-associated pneumonia (HCAP) are important causes of morbidity and mortality despite improvements in supportive care and prevention. Optimal outcomes of these infections rely on timely and appropriate management strategies. However, despite advances in general knowledge, mortality for many of these infections remains high. It is appropriate therefore that new approaches to management of pneumonia be explored with the hopes that such strategies will lead to better outcomes in the future. This chapter considers newer approaches to management and prevention that include new antimicrobials, novel methods of administration of antimicrobials, and new approaches to modification of the host response and prevention.
