ABSTRACT
N-methyl-D-aspartate (NMDA) and dopamine (DA) receptors and their interactions control an incredible variety of functions in the intact brain and, when abnormal, these interactions underlie and contribute to numerous disease states. These receptor interactions are relevant in such diverse functions as motor control, cognition and memory, neurodegenerative disorders, schizophrenia, and addiction. It is thus not surprising that a wealth of information has been generated by the neuroscience
3.1 Introduction ..................................................................................................... 41 3.2 Classification and Morphological Basis for Interactions among
Glutamate and DA Receptor Subtypes ............................................................ 42 3.3 DA and D1 Receptor Enhancement of NMDA Receptor-Mediated
Responses ........................................................................................................ 43 3.3.1 Interactions through Second Messengers ............................................ 43 3.3.2 Physical DA-NMDA Receptor Interactions ........................................44
