ABSTRACT

Obesity is associated with a chronic inflammatory state that contributes to the development of various metabolic and cardiovascular diseases. Adipose tissue has the ability to produce and secrete a variety of bioactive molecules such as adipokines that can regulate the inflammatory responses of several obesity-related complications [1]. Many of these pro-inflammatory adipokines such as leptin [2], resistin [3], C-reactive protein (CRP) [4], tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) [5] are increased in obesity and may promote obesity-linked metabolic and cardiovascular diseases.