ABSTRACT

Amino acid-derived antibiotic. Isol. from the sponge Ianthella ardis and Pseudoceratina crassa. Shows antibacterial and antifungal props. Pale yellow powder. Mp 113-1158. Litaudon, M. et al., Tet. Lett., 1986, 27, 4455

(isol, ir, pmr, cmr, ms, struct)

OMe BrBr

HO

N O H

N O

O

Br

Br COOH

C22H23Br4N3O7 761.056 Alkaloid from the marine sponge Ianthella sp. Cryst. (MeOH aq.). Mp 1541578. [a]22D -97 (c, 0.58 in MeOH). lmax 207 (e 45400); 283 (e 7300) (MeOH). 20-Epimer, N20-di-Me: Ianthesine A

C24H27Br4N3O7 789.109 Alkaloid from Ianthella sp. Cryst. (MeOH aq.). Mp 154-1568. [a]22D -118 (c, 1 in MeOH). lmax 210 (e 29500); 283 (e 7390) (MeOH).