ABSTRACT

The improvements in sensitivity and resolution recorded in nuclear magnetic resonance (NMR) methods over the last years have strongly accelerated the pace at which natural products (NPs) are identied. Within these different technological advances, modications in magnet technology and electronics have led to a smooth but steady development over the years, while the application of more sensitive probe heads such as microcoils or cryogenically cooled probe heads and the application of pulsed eld gradients have resulted in more dramatic changes [1].