ABSTRACT
This group of alkaloids is structurally based on 2-phenylethylamine, which was isolated together with its N-methyl derivative from Accacia prominent. Many analogues of phenylethylamines are hallucinogenic substances that exist naturally but can also be produced synthetically. As regards hallucinogenic phenylethylamines, mescaline is one of greatest importance. This is the main alkaloid of the cactus Lophophora williamsii, better known as peyote, whose native region extends along the southwestern United States. As a classic hallucinogen, it is often used as the potency standard
32.1 Phenylethylamine Derivatives ............................................................................................ 823 32.1.1 Classication of Phenylethylamine Derivatives .................................................... 823 32.1.2 Sample Preparation ............................................................................................... 825 32.1.3 Chromatographic Systems for Separation of Phenylethylamine Derivatives ....... 828 32.1.4 Enantioselective Chromatographic Methods ........................................................ 834 32.1.5 HPLC-MS ............................................................................................................. 836
32.2 Quinoline Derivatives ......................................................................................................... 837 32.2.1 Cinchona Alkaloids .............................................................................................. 837
32.2.1.1 Extraction Procedures .......................................................................... 837 32.2.1.2 Separation Methods ............................................................................. 837 32.2.1.3 Detection of Alkaloids in HPLC Analysis .......................................... 838 32.2.1.4 Cinchona Alkaloids as Chiral Selectors ..............................................840
