ABSTRACT

Polyacetylenes belong to a class of molecules containing two or more triple bonds and constitute a distinct group of relatively unstable, reactive, and bioactive natural products. Polyacetylenes are widespread in nature, occurring in plants, fungi, lichens, moss, microorganisms, algae, and marine invertebrates [1-9]. The triple bond functionality of polyacetylenes makes these natural products a very interesting group of compounds whose reactivity toward proteins and other biomolecules may explain their wide variety of bioactivities.