ABSTRACT

Most inflammatory and degenerative processes include oxygen activating pro-

cesses where reactive oxygen species, ROS, are produced. Intrinsic radical

scavenging systems or compounds administered with food such as Vitamin C

and E, carotenoids and polyphenols, warrant metabolic control within certain

limits. Many of these are free radical scavengers or quenchers of activated states

and operate additively or synergistically. In this review mechanisms of cataract

formation and also of protection from oxidative damage by antioxidants, present

in many plant extracts used as natural drugs, are summarized. For this purpose,

principles of oxygen activation during cataract induction and protective actions

of antioxidants are outlined in short.