ABSTRACT
A. Skin Nerve Anatomy The integument of the body is innervated by large, cutaneous branches of musculocutaneous nerves that arise segmentally from the spinal nerves. In the face, branches of the trigeminal nerve are responsible for cutaneous innervation. The main nerve trunks enter the subcutaneous fat tissues, divide, and form a branching network at the dermal-subcutaneous junction. This deep nervous plexus supplies the deep vasculature, adnexal structures, and sensory receptors. Subsequently, the nerve fibers reorganize into small nerve bundles, which ascend along with the blood vessels and lymphatic vessels to form a network of interlacing nerves beneath the epidermis (i.e., the superficial nerve plexus of the papillary dermis) (2).
