ABSTRACT
Biological functions of the human large intestine include waste storage and the absorption of
water as well as essential minerals. However, because of a slow transit time, near-neutral pH
and substrate availability, the colon harbors a very complex and diverse bacterial micro-
flora.[1] The bacterial microbiota in the human large intestine is thought to compromise
95% of the total cells in the body, representing 1012 cells/g dry weight contents. Through the activities of the resident microflora, the colon plays a major role in host nutrition and
welfare.[2] Dietary modulation of the human gut flora can be of great benefit to health.
In recent years, the functional food concept has moved away from mineral and vitamin
supplementation towards the situation where improved gut (microbial) functionality is
the main current driving force. The colon is the most intensely populated region of the
gastrointestinal tract and is therefore the main target for such dietary intervention.
