ABSTRACT

DOSE PAINTING WITH INTENSITY-MODULATED RADIATION THERAPY: THE RADIOBIOLOGICAL TARGET

The latest available technology in radiation therapy,

intensity-modulated radiation therapy (IMRT), offers

more precise radiation delivery with high dose to target

volume while sparing nearby critical structures. IMRT is

defined as the radiation delivery technique that uses radi-

ation fields of various sizes whose intensity could be varied

to control the dose distributions that could be tailored to fit

complex geometric arrangement of targets and for avoid-

ance of critical structures. By allowing the intensity within

the target to vary opened the door to the possibility of

protecting critical structures that were positioned near the

target and fell within one or more of the different treatment

fields, as well as “paint” or “sculpt” high-/low-dose regions

within the target.