ABSTRACT
The individual and societal costs of cigarette smoking are considerable, including over 5 million deaths per year worldwide (1). Because of the spreading tobacco epidemic in developing nations, projections of tobacco-attributable deaths may get double within the next 25 years (1). Although the prevalence of smoking has been increasing globally, some developed nations such as the United States have seen declining rates of tobacco use in recent years (2). The availability of new pharmacotherapies to aid smoking cessation has likely contributed to this decrease in the prevalence of smoking, but with the long-term success rates of quit attempts bordering on 5% (3), it is clear that there are many challenges still remaining in the effort to help current smokers quit.
