ABSTRACT
Dermatomyositis – calcinosis cutis; white papules resembling malignant atrophic papulosis JAAD 36:317-319, 1997 Graft vs. host disease, chronic – lichen sclerosus-like lesions JAAD 53:591-601, 2005; AD 138:924-934, 2002 Lupus erythematosus – white papules resembling malignant atrophic papulosis (Degos’ disease) JAAD 36:317-319, 1997; Dermatologica 175:45-46, 1987; BJD 95:649-652, 1976; Arch Int Med 134:321-323, 1974; nodular episcleritis Morphea – white plaque; guttate morphea Rook p.2504-2508, 1998, Sixth Edition Rheumatoid nodule Scleroderma – white papules resembling malignant atrophic papulosis (Degos’ disease) Cutis 75:101-104, 2005; JAAD 36:317-319, 1997; AD 100:575-581, 1969; ivory subcutaneous nodules of trunk and extremities BJD 101:93-96, 1979; calcinosis
Bohn’s pearls (milia) of the neonate Calcinosis cutis of the ear, congenital JAAD 49:117-119, 2003 Cartilaginous rest of the neck, congenital Cutis 58:293-294, 1996 Epstein’s pearls – keratinous cysts of palatal or alveolar mucosa in neonates Int Dent J 27:261-262, 1988 Urethral retention cyst – white papule at urethral opening of males Textbook of Neonatal Dermatology, p.483, 2001
Elastotic nodules of the ear JAAD 50:100, 2004; Cutis 44:452-454, 1989
Lichen planus
Foreign body granuloma Silicone granuloma
Adiaspiromycosis – cutaneous adiaspiromycosis (Chrysosporium species) – hyperpigmented plaque with white-yellow papules, ulcerated nodules, hyperkeratotic nodules, crusted nodules, multilobulated nodules JAAD S113-117, 2004 Coxsackie A16 – Koplik’s spots Ghatan p.249, 2002, Second Edition Echovirus 9 – Koplik’s spots Ghatan p.249, 2002, Second Edition Epidermodysplasia verruciformis Maggots Clin Inf Dis 35:1566-1571, 2002 Measles – Koplik’s spots Tyring p.407-408, 2002; Rook p.3102, 1998, Sixth Edition Molluscum contagiosum, including molluscum folliculitis BJD 142:555-559, 2000
Parvovirus B19 – Koplik’s spots Rook p.3102, 1998, Sixth Edition Syphilis – condyloma lata – white moist papules Rook p.1247, 1998, Sixth Edition Tungiasis
Cutaneous mucinosis of infancy – day 1-6; firm grouped white to translucent papules of arms, hands, and trunk; may be linear AD 119:272-273, 1983; AD 116:198-200, 1980 Sarcoid Scleromyxedema JAAD 33:37-43, 1995 Self-healing juvenile cutaneous mucinosis AD 131:459-461, 1995
Calcinosis cutis – idiopathic Rook p.2665, 1998, Sixth Edition; papular or nodular calcinosis cutis secondary to heel sticks Textbook of Neonatal Dermatology, p.112, 2001; Ped Derm 18:138-140, 2001; cutaneous calculus BJD 75:1-11, 1963; extravasation of calcium carbonate or gluconate solution Textbook of Neonatal Dermatology, p.111, 2001; metastatic calcification – deposition of calcium in the media of blood vessels – extensive bone destruction, milk-alkali syndrome, primary or secondary hyperparathyroidism, primary hypoparathyroidism, pseudohypoparathyroidism, chronic renal failure, sarcoid, vitamin D intoxication JAAD 33:693-706, 1995; Cutis 32:463-465, 1983; milia-like calcinosis cutis in Down’s syndrome Ped Derm 19:271-273, 2002; heel sticks Cutis 32:65-66, 1983; vaginal nodules due to urinary incontinence BJD 150:169-171, 2004 Calcium oxalate – distal digital white papule Calcium phosphate Gout – tophus – monosodium urate Cutis 64:233-236, 1999; AD 134:499-504, 1998 Idiopathic calcinosis of the scrotum Br J Plast Surg 42:324-327, 1989; Eur Urol 13:130-131, 1987; Int J Derm 20:134-136,1981; AD 114:957, 1978; dystrophic calcinosis of benign epithelial cyst BJD Miliaria – giant centrifugal miliaria profunda – white papule Osteoma cutis – primary osteoma cutis including multiple osteomas, congenital plate-like osteoma cutis, multiple miliary facial osteomas, Albright’s hereditary osteodystrophy, and fibrodysplasia ossificans progressiva BJD 146:1075-1080, 2002; JAAD 38:906-910, 1998 Progressive osseous heteroplasia – papules and nodules J Bone Joint Surg Am 76:425-436, 1994 Pseudogout – pseudotophi (calcium pyrophosphate) Rook p.2653, 1998, Sixth Edition Renal disease, chronic – nodular calcinosis Ghatan p.176, 2002, Second Edition
Acrochordon Anal intraepithelial neoplasia – perianal hyperpigmented patches, white and/or red plaques JAAD 52:603-608, 2005 Basal cell carcinoma Bowenoid papulosis – vulvar whitish papules or plaques Cancer 57:823-836, 1986 Clear cell papulosis Ped Derm 14:380-382, 1997; JAAD 33:230-233, 1995
Connective tissue nevus Ped Derm 22:153-157, 2005; eruptive collagenomas in pregnancy JAAD 53:S150-153, 2005 Desmoplastic trichoepithelioma – single papule Cancer 40:2979-2986, 1977; multiple familial JAAD 39:853-857, 1998 Epidermoid cyst Rook p.1667, 1998, Sixth Edition Eruptive vellus hair cysts – skin-colored, red, white, blue, yellow eyelid papules Ped Derm 19:26-27, 2002 Large cell acanthomas – white to red flat-topped papules JAAD 53:335-337, 2005 Leiomyoma Leiomyosarcoma – blue-black; also red, brown, yellow or hypopigmented JAAD 46:477-490, 2002 Marginal cysts of eyelids – occluded glands of Moll; painless white or yellow cyst of lower eyelid close to lacrimal punctum Rook p.2987, 1998, Sixth Edition Melanocytic nevus – atypical nevi, non-pigmented AD 113:992-994, 1997 Melanoma – desmoplastic melanoma Metastatic carcinoma Milia, including multiple eruptive milia – face, earlobe Rook p.1669, 1998, Sixth Edition; JAAD 37:353-356, 1997; Cutis 60:183-184, 1997; Clin Exp Dermatol 21:58-60, 1996; after blistering (epidermolysis bullosa, EBA, bullous lupus erythematosus) or trauma (porphyria cutanea tarda, friction) Neuroma (solitary neurofibroma) Rook p.2363, 1998, Sixth Edition; palisaded encapsulated neuroma AD 140:1003-1008, 2004 Nevus sebaceus Osteochondroma – white-yellow nodule Derm Surg 27:591-593, 2001 Perforating follicular hybrid cyst (pilomatrixoma and steatocystoma) of inner eyelid (tarsus) JAAD 48:S33-34, 2003 Persistent actinic epidermolytic hyperkeratosis – hypopigmented papules J Cutan Pathol 6:272-279, 1979 Pilar cyst, calcified Pilomatrixoma – papule with white inclusions Eyelid and Conjunctival Tumors, Shields JA and Shields CL, Lippincott Williams and Wilkins p.71, 1999 Porokeratosis of Mibelli – white plaque JAAD 52:553-555, 2005 Reactive fibrous papule of the fingers (giant-cell fibroma) – fingers and palms Dermatologica 143:368-375, 1971 Retention cyst from glands of Zeis Rook p.2987, 1998, Sixth Edition Sclerotic fibromas of the skin JAAD 20:266-271, 1989 Seborrheic keratosis, irritated Stucco keratoses Syringomas, vulvar – discrete white cystic papules JAAD 48:735-739, 2003 Trichodiscoma – hypopigmented papules AD 126:1093,1096, 1990 Trichoepithelioma Tumors of the follicular epithelium, multiple eruptive – hypopigmented papules of the face and extremities AD 135:463-468, 1999; JAAD 39:853-857, 1998 White fibrous papulosis of the neck BJD 127:295-296, 1992
Actinic lichen planus AD 135:1543-1548, 1999
Acne vulgaris – closed comedones (whiteheads) Rook p.1949-1951, 1998, Sixth Edition; osteoma cutis Ghatan p.258, 2002, Second Edition Albopapuloid epidermolysis bullosa Anetoderma Clear cell papulosis – hypopigmented macules and slightly elevated 1-10-mm papules along milk line on lower abdomen and pubic area Ped Derm 22:268-269, 2005; Ped Derm 14:380-382, 1997 Epidermolysis bullosa, dominant dystrophic; epidermolysis bullosa, albopapuloidea (Pasini) – ivory white papules BJD 146:267-274, 2002 Epidermolysis bullosa pruriginosa – reticulate scarring, dermatitis with lichenified plaques, violaceous linear scars, albopapuloid lesions of the trunk, prurigo nodularis-like lesions, milia BJD 152:1332-1334, 2005 Eruptive tooth Focal epithelial hyperplasia (Heck’s disease) Tyring p.273, 2002 Frictional dermatitis of children – pinhead-sized white papules or warty lesions of backs of hands, elbows, and knees Rook p.895-896, 1998, Sixth Edition Granuloma annulare Lichen nitidus Lichen planus – perianal Rook p.3170, 1998, Sixth Edition Lichen sclerosus et atrophicus Rook p.2549-2551, 1998, Sixth Edition; guttate variant; of the scalp BJD 103:197-200, 1980 Lichen striatus Micaceous and keratotic pseudoepitheliomatous balanitis Bull Soc Fr Dermatol Syphiligr 68:164-167, 1966 Nevus anelasticus Ped Derm 22:153-157, 2005 Papular acantholytic dyskeratosis of the vulva Ped Derm 22:237-239, 2005 Papular elastorrhexis – non-follicular white papules Ped Derm 22:153-157, 2005; Ped Derm 19:565-567, 2002; JAAD 19:409-414, 1988 Perifollicular elastolysis – gray or white follicular papules of neck, earlobes JAAD 51:165-185, 2004 Pseudoxanthoma elasticum-like papillary dermal elastolysis AD 136:791-796, 2000; JAAD 26:648-650, 1992 Psoriasis Reactive perforating collagenosis White fibrous papulosis of the neck JAAD 51:165-185, 2004; Clin Exp Derm 16:224-225, 1991; JAAD 20:1073-1077, 1989
Albright’s hereditary osteodystrophy – osteoma cutis Ghatan p.258, 2002, Second Edition Birt-Hogg-Dube syndrome – trichodiscomas JAAD 48:111-114, 2003; AD 113:1674-1677, 1977 Buschke-Ollendorff syndrome – connective tissue nevi and osteopoikilosis; single or multiple yellow, white, or skin-colored papules, nodules, plaques of extremities JAAD 48:600-601, 2003; BJD 144:890-893, 2001 Dermochondrocorneal dystrophy – white nodules of feet Caputo p.56, 2000 Down’s syndrome – milia-like idiopathic calcinosis cutis BJD 134:143-146, 1996 Fibrodysplasia ossificans progressiva – osteoma cutis Ghatan p.258, 2002, Second Edition
Hunter’s syndrome – white to skin-colored papules over scapulae, shoulders, upper arms, chest, thighs, and nape of neck; sometimes arranged in linear ridges and plaques, or cobblestoned Ped Derm 7:150, 1991; AD 113:602-605, 1977 Hurler’s syndrome Juvenile hyaline fibromatosis – pearly white papules of face and neck; larger papules and nodules around nose, behind ears, on fingertips, multiple subcutaneous nodules of scalp, trunk, and extremities, papillomatous perianal papules; joint contractures, skeletal lesions, gingival hyperplasia, stunted growth Textbook of Neonatal Dermatology, p.444-445, 2001 Lipoid proteinosis – yellow-white papules of tongue, lips, pharynx Int J Derm 39:203-204, 2000; JAAD 27:293-297, 1992 Oral-facial-digital syndrome – white nodules of tongue Tuberous sclerosis – connective tissue nevus
Extruding tooth – white papule Cutis 54:253-254, 1994 Piezogenic pedal papules AD 106:597-598, 1972 Scar Weathering nodules of the ear BJD 135:550-554, 1996
Degos’ disease JAAD 37:480-484, 1997; AD 122:90-91,93-94, 1986; Ann DV 79:410-417, 1954
XANTHOMATOUS LESIONS Alagille syndrome – triangular facies, cardiovascular anomalies (peripheral pulmonary stenosis), butterfly-like vertebral arch defects, ocular abnormalities Ped Derm 15:199-202, 1998 APO E11/E111 phenotype Cerebrotendinous xanthomatosis CHILD syndrome – xanthomatous pattern Dermatologica 180:263-266, 1990 Epidermolysis bullosa, dystrophica – verruciform xanthoma Eruptive xanthoma Cutis 50:31-32, 1992 Hereditary tendinous and tuberous xanthomas High-density lipoprotein deficiency Hyperapoprotein B Langerhans cell histiocytosis – xanthoma-like cutaneous lesions in an adult JAAD 34:688-689, 1996 Lymphoma – B-cell lymphoma – xanthomatous infiltration of the neck Eur J Derm 10:481-483, 2000; papular xanthomatosis JAAD 26:828-832, 1992; dystrophic xanthoma in cutaneous T-cell lymphoma AD 123:91-94, 1987; xanthomatous CTCL AD 128:1499-1502, 1992 Normocholesterolemic dysbetalipoproteinemia Normocholesterolemic xanthomatosis AD 122:1253-1257, 1986 Normolipemic eruptive xanthomas Normolipemic papular xanthomas – in erythrodermic atopic dermatitis JAAD 32:326-333, 1995 Normolipemic plane xanthomas – multiple myeloma; Castleman’s syndrome JAAD 39:439-442, 1998; JAAD 26:105-109, 1991; relapsing polychondritis Acta DV 74:221-223, 1994 Normolipemic subcutaneous xanthomatosis
Normolipemic tendinous and tuberous xanthomas Papular xanthomas Beta sitosterolemia Serum lipoprotein deficiency Titanium dioxide pigmentation – plane xanthoma-like lesion AD 121:656-658, 1985 Verruciform xanthoma JAAD 42:343-347, 2000; Am J Surg Pathol 22:479-487, 1998 Wegener’s granulomatosis – yellow eyelid papules (florid xanthelasmata) JAAD 37:839-842, 1997; Br J Ophthalmol 79:453-456, 1995; Eyelid and Conjunctival Tumors, Shields JA and Shields CL, Lippincott Williams and Wilkins p.167, 1999 Xanthoma disseminatum NEJM 338:1138-1143, 1998; Clin Investig 7:233-238, 1993; JAAD 23:341-346, 1990; AD Syphilol 37:373-402, 1938 Xanthomas following erythroderma
Graft vs. host disease JAAD 53:591-601, 2005 Lupus erythematosus Ghatan p.267, 2002, Second Edition Sjögren’s syndrome – anhidrosis JAAD 16:233-235, 1987; xerosis Rook p.2571, 1998, Sixth Edition
Senescence BJD 122 Suppl 35:97-103, 1990 Sympathetic nerve dystrophy – anhidrosis with xerosis Rook p.2780, 1998, Sixth Edition
Beta blockers The Clinical Management of Itching; Parthenon; p.35, 2000 Busulfan The Clinical Management of Itching; Parthenon; p.35, 2000 Cetuximab JAAD 53:291-302, 2005 Cimetidine AD 118:253-254, 1982 Clofazamine Ghatan p.267, 2002, Second Edition Clofibrate The Clinical Management of Itching; Parthenon; p.35, 2000 Diazocholesterol Ghatan p.267, 2002, Second Edition Fenretinide Clin Can Res 9:2032-2039, 2003 Flutamide Ghatan p.267, 2002, Second Edition Hydroxyurea AD 135:818-820, 1999; AD 111:183-187, 1975 Indinavir (protease inhibitor) JAAD 46:284-293, 2002 Interferon-α Semin Oncol 14:1-12, 1987 Itraconazole – photodermatitis and retinoid-like dermatitis J Eur Acad Dermatol Venereol 14:501-503, 2000 Lithium carbonate AD 111:1073-1074, 1975 Nafoxidine The Clinical Management of Itching; Parthenon; p.35, 2000 Niacin The Clinical Management of Itching; Parthenon; p.35, 2000 PUVA J Formosa Med Assoc 98:335-340, 1999
Retinoid dermatitis – isotretinoin, etretinate, acetretin Clin Pharm 2:12-19, 1983 Tamoxifen The Clinical Management of Itching; Parthenon; p.35, 2000 Triparanol Ghatan p.267, 2002, Second Edition Vitamin A excess Exp Eye Res 7:388-393, 1968 Voriconazole – photodermatitis and retinoid-like dermatitis Ped Derm 21:675-678, 2004; Pediatr Infect Dis J 21:240-248, 2002; Clin Exp Dermatol 26:648-653, 2001
Chloracne Clin Exp Dermatol 18:523-525, 1993 Cryosurgery Arch Ophthalmol 99:460-463, 1981 Dry environment BJD 149:240-247, 2003 Irritant contact dermatitis – resembles xerosis Rook p.721, 1998, Sixth Edition Kava dermopathy – xerosis with scaly yellow pigmentation JAAD 53:S105-107, 2005; JAAD 31:89, 1994 Water sports Fitzpatrick, p.1253 Winter Fitzpatrick, p.1213
