ABSTRACT
Bronchopulmonary dysplasia (BPD) was originally described by Northway and collaborators in the late-1960s as a complication of aggressive mechanical respiratory support in preterm infants with severe respiratory distress syndrome (RDS) (1). Despite the considerable advances in the prevention and management of RDS that have occurred in the last two decades, BPD remains as one of the major complications in premature infants who require prolonged mechanical ventilation (2,3). In fact, the increasing survival of the most immature infants has produced an increase in the number of survivors with BPD (4-9).
