ABSTRACT
Age-appropriate drug formulations are a challenge in drug development. A critical review
of available drugs shows that a number of marketed products cannot be easily used for
pediatric or geriatric patients who differ in many aspects from the “adult standard patient”
(1). It is well known that the human body undergoes fundamental changes from birth to
death. In childhood the maturation of organs and consciousness is the predominant factor
that influences drug therapy. In the advanced life the diminution of organs’ capacity and
functions and additionally the reduced cognitive abilities of some elderly limit the
effective and safe treatment with drugs. Although the pediatric and geriatric
subpopulations show fundamental differences to be considered, there are a number of
similarities not only concerning the drug delivery, the devices, and the drug formulations
but also special demands of the patients. Recent technological developments are
promising. The present chapter includes well-established methods and future trends for
drug delivery to both subpopulations.
