ABSTRACT

This ability of ICP-MS to carry out isotopic measurements allows the technique to carry out quantitation methods that are not available to any other trace element technique. They include the following:

Quantitative analysis• Semiquantitative routines• Isotope dilution• Isotope ratio• Internal standardization•

Each of these techniques offers varying degrees of accuracy and precision; so, it is important to understand their strengths and weaknesses to know which one will best meet the data quality objectives of the analysis. Let us look at each of these in greater detail.