ABSTRACT
The antibacterial potency of the analogs had been measured in a whole-cell turbidometric assay, which follows the growth of bacteria in the presence and absence of an antibiotic. The raw potency was reported on a milligram basis relative to erythromycin A, which was assigned a potency of 1000. For the QSAR analysis, we corrected the relative potencies for the differences in molecular weight and used a logarithm of the corrected potency for the variable log (1/CSA).
